New publication in Science using semiautomated patch clamp

Yangfan Peng and colleagues in the lab of Jörg Geiger at the Charité in Berlin (Germany) just published an exciting paper in which they discovered that neural networks in human cerebral cortex follow fundamentally different connectivity patterns than those found in rodent neocortex. Building computational network models based on these newly discovered connectivity rules lead to a substantial  increase in network dynamics dimensionality.

To assess a total of 7200 connections, the team used semi-automated patch clamp recordings, including the reuse of pipettes after cleaning. Sensapex are proud to have been able to provide the micromanipulators that made such a major data acquisition feat possible.

For full details see:  https://www.science.org/doi/10.1126/science.adg8828

A patch clamp rig for simultaneous recordings from up to ten neurons (Image kindly provided by the lab or Prof. Jörg Geiger, Charité Berlin).

Sensapex have extended their representation in Europe, by adding Scop Pro as an  additional distribution partner in France. Having a long history of working closely with neuroscientists and physiologists all over France, we are happy to see them adding Sensapex technology to their catalogue.

Sensapex will happy to return to Washington DC for another SfN Neuroscience meeting November 12 to 15.

For the first time ever, we will have our newly launched Multiprobe In Vivo Rig on display. We are happy to be able to show this with full integration in Pinpoint, making planning of multiprobe in vivo recordings easier than ever before.

In addition we will be showing our uM-Patch workstations, including a new option to upgrade existing upright microscopes.

Finding your way in the brain – Using Pinpoint to perform efficient and reproducible electrophysiology experiments

Presenter: Daniel Birman (University of Washington, Seattle, USA)
Date: Wednesday, October 25, 2023
Time: 9 AM Seattle, WA (PDT), 12:00 PM New York (EDT), 6 PM Berlin, 5 PM London, UK (BST), Germany (CEST)

Together with our distribution partner NPI Electronic, we will be hosting Dan Birman of the University of Washington. Dan will be presenting Pinpoint, a software suite that he has co-developed. He will be providing a detailed introduction into using Pinpoint to plan in vivo multiprobe recordings.

Join us for this exciting and useful session! Register here

In response to valuable feedback from our customers, Sensapex has taken considerable steps to enhance its support services. We are proud to announce the establishment of our first-response customer support center in Fort Mill, SC. This center will serve as the primary interface for our US customers, offering immediate assistance and first-level repair services.

We are also delighted to introduce you to Paul Koch, our dedicated US customer service engineer. Paul brings with him a wealth of experience and is committed to ensuring the highest standards of service for our customers.

tel. 1-800-284-9784
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Less than four weeks until we will be at the 2023 NWG meeting. We feel a special connection to the Göttingen meeting, because this is where we introduced our first ever micromanipulator to the neuroscience community back in 2011.

If you are going to be there, drop by our booth – Matti Rautiainen and Christian Wilms look forward to chatting about your experiments and are happy to show you our full patch-clamp rigs with automated – including our automatic pipette cleaning.

Neuroscience 2022 will take place November 12-16 at the San Diego Convention Center in San Diego, CA.

Please visit our booth #2618 and test completely new uMs-FN1 microscope workstation. New uMs-FN1 workstation provides motorized objective exchange, closed-loop controlled focus and stage and full integration with Sensapex uMp-micromanipulators.

Please visit our booth #275 and test completely new uMs-AXE microscope workstation. New uMs-AXE workstation provides motorized objective exchange, closed-loop controlled focus and stage and full integration with Sensapex uMp-micromanipulators.

Sensapex is pleased to support Microelectrode Techniques for Cell Physiology Workshop in Marine Biological Association in Plymouth, UK. Workshop starts at 28th of August and lasts until 11th of September, Sensapex micromanipulators being used for several set-ups.

Sensapex has the privilege to provide micromanipulators for CAJAL Neuroscience Training Course 2019 in Champalimaud Center for the Unknow, Lisbon, Portugal. Course lasts four weeks staring from 1st of July and provides high-level teaching about interacting with neural circuits.