Pressure control for automated patch clamping

The uMc-PPC pressure controllers are designed to simplify and automate frequent tasks in patch clamp experiments. From cleaning the membrane and forming a seal, over breaking into a cell, to automatic cleaning of patch pipettes after a patch attempt, the sensitivity and accuracy that these automated pressure controllers are up to the challenge. The accuracy and fine resolution that the uMc-PPC series provide, bring a new level of reproducibility to patch clamp electrophysiology.

Why choose the uMc-PPC series?

Sensapex Pressure Control Products

• The uMc-PPC units allow for pressure control over a range of +/- 100 kPa with 10 Pa resolution – enough range and precision for reliable automation of all steps in patch clamping.
• With repeatability and absolute accuracy both better than 0.5 kPa, the uMc-PPC guarantees that the pressure levels and sequences you set are the ones you get. For approach, seal formation, and break-in. Every time.
• The ability to switch between user controlled and automated pressure in just 4 ms ensures that you stay in full control of your experiment.
• All uMc-PPC devices are fully integrated into the Sensapex control environment, allowing easy set up and control from either the touch screen unit or through the SDK for advanced automation.

We facilitate new discoveries

Sensapex has had the privilege to provide products to more than 1000 labs worldwide. We are regularly surprised and impressed by the clever way in which our manipulators are used for experiments. Often in ways that we never imagined. Our ever-growing list of References showcases some of the amazing work being done with our instruments.

Configuration examples

Sensapex products are proprietary and patented (US 9,138,892, US 9,662,783, EP 2 776 215, US 10,427,292; EP 09851052.2, EP15906190.2, US 15/765,608, EP: 15906189.4). Automated patch clamp (US 9,498,293 and US 9,668,804) and pipette cleaning (US 15/232,770 and EP 16836035.2) products are manufactured under licenses from GTRC and MIT, U.S.A.